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How Bellafill Works

80-collagen--20-pmmaBellafill® uses an innovative blend of 2 distinct components to create results that are both immediate and long lasting. Suspended within its smooth collagen gel base are tiny polymethyl methacrylate (PMMA) microspheres. Once it’s injected, the collagen goes to work immediately, adding natural-looking volume to soften smile lines or acne scars. Over time, your body naturally metabolizes the collagen — but that doesn’t mean your results disappear. The PMMA microspheres work as a scaffolding system, supporting the development of your own collagen and laying the foundation for long-term smoothness. With Bellafill®, you don’t have to decide between looking great now and looking great later.

Upon injection, the collagen gel in Bellafill® adds instant volume to your lines or acne scars.

Over time, your own collagen and other tissue uses the PMMA microspheres as support for long-lasting smoothness

Youthful Looks That Last

Cari’s Testimonial

Bellafill® for Smile Lines

Eventually, facial aging catches up with us all. Although dermal fillers are often the preferred treatment for lines and wrinkles, many of them yield results that are temporary and require repeat touch-ups in order to last. Bellafill® is a different type of filler. Its ingredients provide volume that’s both instant and lasting — so you don’t have to decide between looking great now and looking great later.

Beautiful, natural-looking results for smile lines.




Individual Results May Vary

Cosmetic Mechanism of Action

Cosmetic Testimonial

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Bellafill® for Acne Scars

Although your acne may be long gone, its scars can hang around. Bellafill®fades these scars by adding volume to them, bringing them to the level of the surrounding skin and keeping them there through 1 year. Bellafill® is the first and only injectable filler that’s FDA approved to treat acne scars.

Beautiful, natural-looking results for acne scars.




Individual Results May Vary


Acne Scar
Patient Testimonials

How Can Bellafill® Help?

Unlike hyaluronic acid fillers, which often dissolve within a few months, Bellafill® creates a lasting improvement in your skin. Its tiny, polymethyl methacrylate (PMMA) microspheres are suspended within a base of smooth collagen gel. Once injected, Bellafill® immediately reduces the look of smile lines. Over time, your body uses the microspheres to create a “scaffold” onto which your own collagen can develop.1,2 This collagen forms a foundation that adds volume to wrinkles, reducing their appearance. These natural-looking results feel soft and smooth through 5 years.

Bellafill® is placed below the depression using a fine needle.

The injectable gel immediately adds volume to the skin to lift and smooth out wrinkles.

Important Safety Information

Bellafill® is indicated for the correction of nasolabial folds and moderate to severe, atrophic, distensible facial acne scars on the cheek in patients over the age of 21 years. Patients who have had a positive reaction to the Bellafill® Skin Test, have a history of severe allergies, have known bovine collagen allergies, are allergic to lidocaine, have bleeding disorders or are prone to thick scar formation and/or excessive scarring should not receive Bellafill®. The safety of Bellafill® for use during pregnancy, breastfeeding, or in patients under 21 has not been established. You may experience temporary swelling, redness, pain, bruising, lumps/bumps, itching, and discoloration at the treatment site. These side effects are usually transient and typically resolve within 1–7 days. You may experience lumps/bumps/papules that may occur more than one month after injection and that may persist. Less common side effects include rash and itching more than 48 hours after treatment, persistent swelling or redness, lumps/bumps, acne, and increased sensitivity at treatment sites. Infrequently, granulomas may occur and may be treated by your licensed physician provider. Be sure to call your licensed provider immediately if you notice any unusual skin reactions around the treatment area. Based on the 5-year Post-Approval Study on nasolabial folds with 1,008 patients, long-term safety of Bellafill® for up to 5 years has been established.


  1. Gottfried Lemperle, et. al., ArteFill® Permanent Injectable for Soft Tissue Augmentation: I. Mechanism of Action and Injection Techniques., Aesthetic Plast Surg. 2010 Jun;34(3):264–72.
  2. Bellafill® [Instructions for Use]. San Diego, CA: Suneva Medical, Inc.; 2015.
  3. Jacob CI, Dover JS, Kaminer MS. Acne scarring: A classification system and review of treatment options. J Am Acad Dermatol; July 2001; 109-117.
  4. Data on file. Suneva Medical, Inc.
  5. Haneke et al. Polymethyl Methacrylate Microspheres in Collagen. Semin Cutan Med Surg 23:227-232,2004.
  6. Cohen et al. Artecoll: A Long-Lasting Injectable Wrinkle Filler Material: Report of a Controlled, Randomized, Multicenter Clinical Trial of 251 Subjects. Plast. Reconstr. Surg. 114: 964,2004.
  7. American Academy of Dermatology,
  8. Journal of Plastic, ReconstructiveandAestheticSurgery,2008,
  9. Formula PR Independent Study, 2013.
  10. Suneva Medical AAD Advisory Board, August 2015, data on file. SM 2361-3 REV00 SM 2361-2 REV00″

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